Detalhe da pesquisa
1.
JNJ-73763989 and bersacapavir treatment in nucleos(t)ide analog suppressed patients with chronic hepatitis B: REEF-2.
J Hepatol
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38583491
2.
Randomised phase 2 study (JADE) of the HBV capsid assembly modulator JNJ-56136379 with or without a nucleos(t)ide analogue in patients with chronic hepatitis B infection.
Gut
; 72(7): 1385-1398, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36697207
3.
Combination treatments including the small-interfering RNA JNJ-3989 induce rapid and sometimes prolonged viral responses in patients with CHB.
J Hepatol
; 77(5): 1287-1298, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35870702
4.
Liver safety assessment in clinical trials of new agents for chronic hepatitis B.
J Viral Hepat
; 27(2): 96-109, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31828894
5.
JNJ-4178 (AL-335, Odalasvir, and Simeprevir) for 6 or 8 Weeks in Hepatitis C Virus-Infected Patients Without Cirrhosis: OMEGA-1.
Hepatology
; 69(6): 2349-2363, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30693573
6.
Pharmacokinetic Interactions between Simeprevir and Ledipasvir in Treatment-Naive Hepatitis C Virus Genotype 1-Infected Patients without Cirrhosis Treated with a Simeprevir-Sofosbuvir-Ledipasvir Regimen.
Antimicrob Agents Chemother
; 61(12)2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971875
7.
Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study.
BMC Infect Dis
; 17(1): 389, 2017 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28577353
8.
Virology analyses of HCV isolates from genotype 1-infected patients treated with simeprevir plus peginterferon/ribavirin in Phase IIb/III studies.
J Hepatol
; 62(5): 1008-14, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25445400
9.
Efficacy and safety of simeprevir with PegIFN/ribavirin in naïve or experienced patients infected with chronic HCV genotype 4.
J Hepatol
; 62(5): 1047-55, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25596313
10.
Simeprevir plus sofosbuvir, with or without ribavirin, to treat chronic infection with hepatitis C virus genotype 1 in non-responders to pegylated interferon and ribavirin and treatment-naive patients: the COSMOS randomised study.
Lancet
; 384(9956): 1756-65, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25078309
11.
Telaprevir for retreatment of HCV infection.
N Engl J Med
; 364(25): 2417-28, 2011 Jun 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21696308
12.
Virologic characterization of genotype 4 hepatitis C virus variants in patients treated with telaprevir.
Virol J
; 11: 93, 2014 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24886541
13.
Fatigue during treatment for hepatitis C virus: results of self-reported fatigue severity in two Phase IIb studies of simeprevir treatment in patients with hepatitis C virus genotype 1 infection.
BMC Infect Dis
; 14: 465, 2014 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25164700
14.
Telaprevir activity in treatment-naive patients infected hepatitis C virus genotype 4: a randomized trial.
J Infect Dis
; 208(6): 1000-7, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801602
15.
Evolution of treatment-emergent resistant variants in telaprevir phase 3 clinical trials.
Clin Infect Dis
; 57(2): 221-9, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23575197
16.
Sustained virologic response rates with telaprevir by response after 4 weeks of lead-in therapy in patients with prior treatment failure.
J Hepatol
; 58(3): 488-94, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23183521
17.
Limited impact of IL28B genotype on response rates in telaprevir-treated patients with prior treatment failure.
J Hepatol
; 58(5): 883-9, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23321318
18.
Characterization of telaprevir treatment outcomes and resistance in patients with prior treatment failure: results from the REALIZE trial.
Hepatology
; 56(6): 2106-15, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22806681
19.
Insulin resistance and response to telaprevir plus peginterferon α and ribavirin in treatment-naive patients infected with HCV genotype 1.
Gut
; 61(10): 1473-80, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22387529
20.
Efficacy and safety of the siRNA JNJ-73763989 and the capsid assembly modulator JNJ-56136379 (bersacapavir) with nucleos(t)ide analogues for the treatment of chronic hepatitis B virus infection (REEF-1): a multicentre, double-blind, active-controlled, randomised, phase 2b trial.
Lancet Gastroenterol Hepatol
; 8(9): 790-802, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442152